Abstract: High speed interactive visualization of large-scale mesh datasets for desktop VR facilities is still a challenge because of the slow geometry setup and rasterization for huge number of small triangles. This paper presents a point-based virtual reality (VR) visualization pipeline for large-scale mesh datasets in a client-server architecture. Remote server computation which samples the triangle mesh into discrete 2D grids is steered by the client-end interactive frustum request. A point-based geometry is built up incrementally during run time for both server and client. By organizing the point model into a multi-resolution octree-based space partition hierarchy, the client-end visualization ensures fast view reconstruction by splatting the available points onto the screen with efficient occlusion culling and view-dependent level of detail (LOD) control. The combination of the high-priority client side local splatting and server side low-speed view updating decreases the dependence on remote computation performance and network requirements for an interactive VR visualization.