Abstract: Cardiovascular diseases account for a major cause of deaths in many developed countries. To treat cardiovascular diseases, cardiac minimally intervention is widely used as an effective yet complicated solution. Training of cardiac intervention is thus playing a crucial role. This paper addresses the use of Virtual Reality (VR) technology for the simulated training of cardiac intervention. In particular, the paper describes the architecture of a VR simulation system for cardiac intervention focusing on VR hardware, software and methodology is used in As an enabling technology, Graphics Processing Unit (GPU) is applied in this work to enhance cardiac modeling, cardiac visualization, and cardiac interactive simulation with the VR simulation environment.